Proton Pump Inhibitors may increase the risk of chronic kidney failure

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Proton Pump Inhibitors such as Prilosec, Nexium and Prevacid may increase the risk of chronic kidney failure. If you or a loved one suffered kidney failure or have been diagnosed with chronic kidney disease after daily use of the prescription strength Prilosec or Nexium, or over the counter Prilosec or Nexium (Brand name only) you may be eligible for compensation.

Proton Pump Inhibitors work by blocking acid release into the stomach. They are used to treat gastroesophageal reflux disease (GERD) which may occur in up to 60 percent of the adult population each year. They are also used to treat peptic ulcer disease (PUD) and a number of other stomach conditions such as “heartburn”.

The PPI market is said to be worth upwards of $10 billion annually in the U.S. alone and Nexium (esomeprazole) was the best selling prescription medication in 2012 and number two on the same list in 2013 with annual revenue of nearly $6 billion.

Up to 14 percent of U.S. adults have received prescription PPI medications and all three of the most popular PPIs are now available over-the- counter. Some estimates show that at least 25% of long-term PPI users could discontinue the medications with no adverse events and that many had started taking them with no clear indication.

The February 2016 issue of JAMA, the Journal of the American Medical Association, published results of a study which indicated that long-term use of PPI medications may increase the risk of the development of chronic kidney disease (CKD). The study indicated that the 10-year risk of CKD in PPI users was 20 to 50 percent higher than those who had not taken the medications.

The study also showed that the longer a person takes the medications, the greater the risk and patients who took the medications more than once a day were more likely to develop the condition.

If you have been diagnosed with chronic kidney disease, acute kidney injury, interstitial nephritis, or end-stage renal disease after taking PPIs such as Nexium, Prilosec, or Prevacid, we would like to hear from you. You may be entitled to compensation.